top of page

This site was designed with the

website builder. Create your website today.Start Now

合成有機化學實驗室 Synthetic Organic Chemistry Laboratory

College Student Research Project
大專學生研究計畫

1. 本實驗室吳潔霓同學通過114年度國科會大專生研究計畫(114-2813-C-390-028-M)
2. 本實驗室李和璉同學通過114年度國科會大專生研究計畫(114-2813-C-390-029-M)
3. 本實驗室莊育瑛同學通過113年度國科會大專生研究計畫(113-2813-C-390-038-M)

New

Published Journal
發表之期刊

1. Fu, C.-H., Ajitha, M. J., Kadiyala, V., Wang, Y.-C., Hsu, T.-Y., Sung, I.-H., Huang, K.-W.*,& Chou, C.-M.* Carboxylate-Directed Oxidative Annulation via C(Alkenyl)−H Activation/Double Alkyne Insertion/1,4-Pd Migration: Synthesis of Functionalized Naphthalenes. Adv. Synth. Catal. 2025, 367 (5).

New

1. Fu, C.-H., Ajitha, M. J., Kadiyala, V., Wang, Y.-C., Hsu, T.-Y., Sung, I.-H., Huang, K.-W.*,& Chou, C.-M.* Carboxylate-Directed Oxidative Annulation via C(Alkenyl)−H Activation/Double Alkyne Insertion/1,4-Pd Migration: Synthesis of Functionalized Naphthalenes. Adv. Synth. Catal. 2025, 367 (5).

2. Chang, C.-H., Yen, C.-T., Goncalves, T. P., Lin, Y.-S., Wang, Y.-C., Sidick Basha, R., Chen, B.-Y., Fu, C.-H., Chen, L.-W.,

Jhou, M.-L., Huang, K.-W., & Chou, C.-M.* Substrate-directed regioselective alkene functionalizations of (E)-β,γ-

unsaturated carboxylic acids. Chem. Commun., 2024, 60, 11339

3. Kadiyala, V.; Hsu, H.-F.; Chou, C.-M.* Carboxylic Acid as A Traceless Directing Group for Palladium-Catalyzed

Proaromatic C(alkenyl)–H Arylation. ARKIVOC 2023, (ii) 202312004.

orlef7.2023.25.issue-43.largecover.jpg

4. Wu, Y.-Y.; Wu,Y.-L.*; Lin, C.-L.*; Chen, H.-C.; Chuang, Y.-Y.; Chen, C.-H.*; Chou, C.-M.* Butterfly -

Shaped Dibenz[a,j]anthracenes: Synthesis and Photophysical Properties. Org. Lett. 2023, 25, 7763.

5.Tsai, S.-Y.; Huang, Y.-W.; Chou, C.-M.* Carboxylate-Directed Palladium-Catalyzed Regioselective

Mizoroki−Heck Alkenylation of γ,δ-Unsaturated Carboxylic Acids. Adv. Synth. Catal. 2023, 365,

6.Tsai, J.-J.; Huang, Y.-H.; Chou, C.-M.* Carboxylate-Assisted Palladium-Catalyzed Regio- and

Stereoselective Mizoroki–Heck Arylation of β-Cyclohexadienyl Acrylates and Styrenes. Org. Lett.

2021, 23, 9468.

7. Hsieh, C.-E.; Tsao, C.-Y.; Chuang, C.-H.; Chen, L.-W.; Chou, C.-M.* Palladium-Catalyzed Regiospecific

Decarboxylative Allylation of (Cyclohexadienylidene)malononitriles: Access to α-Allyl-α-aryl

Malononitriles. J. Org. Chem. 2021, 86,12168.

8. Liu, T.-L.; Jhou, M.-L.; Hsieh, C.-E.; Lin, C.-J.; Su, H.-H.; Chou, C.-M.* Palladium-Catalyzed Intramolecular

Allylic Amidation via Decarboxylative Aromatization: Synthesis of N-Allyl-N-aryl Sulfonamides.

J. Org. Chem. 2021, 86,9084.

9. Wang, Y.-C.; Huang, Y.-H.; Tsai, H.-C.; Basha, R. S.; Chou, C.-M.* Palladium-Catalyzed Proaromatic

C(Alkenyl)−H Olefination: Synthesis of Densely Functionalized 1,3-Dienes. Org. Lett. 2020, 22,

10. Hsieh, C.-E.; Jiang, Y.-M.; Chou, C.-M.* Functionalized Allyl Aryl Ether Synthesis from Benzoic Acids

Using aDearomatization and Decarboxylative Allylation Approach. J. Org. Chem. 2019, 84, 653.

11. Chen, C.-H.*; Cao, Y.-T.; Lin, C.-L.; Chou, C.-M.* Controlling Molecular Conformations of Alkyl Bridged

Bis- aminostyrene : Investigation of Inter-chromophore Interaction. J. Mol. Struct. 2018, 1168, 322.

12. Leung, M.-k., Chou, C.-M., Luh, T.-Y.* 1,3-Dithiolanes. Science of Synthesis Knowledge Updates, 2018

13. Luh, T.-Y.*, Leung, M.-k., Chou, C.-M. 1,3-Dithiolanes. Science of Synthesis Knowledge Updates,

14. Chang, C.-H.; Chou, C.-M.* Palladium-Catalyzed Decarboxylative g-Olefination of 2,5-Cyclohexadiene-1-

carboxylic Acid Derivatives with Vinyl Halides. Org. Lett. 2018, 20, 1949.

15. Tsai, H.-C.; Huang, Y.-H.; Chou, C.-M.* Rapid Access to Ortho-Alkylated Vinylarenes from Aromatic

Acids by Dearomatization and Tandem Decarboxylative C-H Olefination/Rearomatization. Org.

Lett. 2018, 20, 1328.

16. Osaki, H., Chou, C.-M., Taki, M., Welke, K., Yokogawa, D., Irle, S., Sato, Y., Higashiyama, T., Saito, S., Fukazawa,

A., & Yamaguchi, S. (2016). A macrocyclic fluorophore dimer with flexible linkers: Bright excimer emission with

a long fluorescence lifetime. Angewandte Chemie (Weinheim an Der Bergstrasse, Germany), 128(25), 7247–

17. Chou, C.-M., Nobusue, S., Saito, S., Inoue, D., Hashizume, D., & Yamaguchi, S. (2015). Highly bent crystals

formed by restrained π- stacked columns connected via alkylene linkers with variable conformations.

Chemical Science (Royal Society ofChemistry: 2010), 6(4), 2354–2359.

18. Lin, T.-W., Chou, C.-M., Lin, N.-T., Lin, C.-L., & Luh, T.-Y. (2014). End group modification of polynorbornenes.

Macromolecular Chemistry and Physics, 215(23), 2357–2364.

19. Chou, C.-M., Saito, S., & Yamaguchi, S. (2014). Heterotriangulenes π-expanded at bridging positions. Organic

Letters, 16(11),2868–2871

20. Chou, C.-M., Chatterjee, I., & Studer, A. (2011). Stereospecific palladium‐catalyzed decarboxylative

C(sp3)-C(sp2) coupling of 2,5‐cyclohexadiene‐1‐carboxylic acid derivatives with aryl iodides. Angewandte

Chemie (International Ed. in English), 50(37), 8614–8617.

21. Chou, C.-M., Guin, J., Mück-Lichtenfeld, C., Grimme, S., & Studer, A. (2011). Radical‐transfer hydroamination of

olefins with N‐ aminated dihydropyridines. Chemistry, an Asian Journal, 6(5), 1197–1209.

22. Lin, H.-C., Hsu, J.-H., Lee, C.-K., Tai, O. Y.-H., Wang, C.-H., Chou, C.-M., Chen, K.-Y., Wu, Y.-L., & Luh, T.-Y. (2009).

Observing second‐order nonlinear optical properties by symmetry breaking in centrosymmetric furan‐

containing oligoaryl cyclophandienes. Chemistry (Weinheim an Der Bergstrasse, Germany), 15(47), 13201–

23. Chou, C.-M., Chen, C.-H., Lin, C.-L., Yang, K.-W., Lim, T.-S., & Luh, T.-Y. (2009). Alternating furanylene-meta-

phenylene oligomers: synthesis and photophysics. Tetrahedron, 65(47), 9749–9755.

24. Chou, C.-M., Lee, S.-L., Chen, C.-H., Biju, A. T., Wang, H.-W., Wu, Y.-L., Zhang, G.-F., Yang, K.-W., Lim, T.-S., Huang,

M.-J., Tsai, P.-Y., Lin, K.-C., Huang, S.-L., Chen, C.-H., & Luh, T.-Y. (2009). Polymeric ladderphanes. Journal of the

American Chemical Society, 131(35), 12579–12585

25. Luh, T.-Y., Lin, H.-C., & Chou, C.-M. (2008). Heterophenes revisited. Pure and Applied Chemistry, 80(3), 475–484.

26. Noguchi, H., Shioda, T., Chou, C.-M., & Suginome, M. (2008). Differentially protected benzenediboronic acids:

Divalent cross-coupling modules for the efficient synthesis of boron-substituted oligoarenes. Organic

Letters,10(3), 377–380.

27. Lin, C.-L., Wu, Y.-L., Chen, C.-L., Chou, C.-M., & Luh, T.-Y. (2007). Sequential electrochemical oxidation of

alternating benzene-furan oligomers. The Journal of Organic Chemistry, 72(22), 8531–8534.

28. Chen, I.-W. P., Fu, M.-D., Tseng, W.-H., Chen, C.-H., Chou, C.-M., & Luh, T.-Y. (2007). The effect of molecular

conformation on single molecule conductance: measurements of π-conjugated oligoaryls by STM break

junction. Chemical Communications (Cambridge, England), 29, 3074–3076.

29. Chou, C.-M., Chen, W.-Q., Chen, J.-H., Lin, C.-L., Tseng, J.-C., Lee, C.-F., & Luh, T.-Y. (2006).Convergent/

divergent synthesis and photophysical studies of alternating benzene–furan oligoaryls from substituted

propargylic dithioacetals. Chemistry, an Asian Journal, 1(1–2), 46–55.

30. Lin, S.-Y., Chen, I. P., Chen, C.-H., Lee, C.-F., Chou, C.-M., & Luh, T.-Y. (2005). Monolayer structures of highly

photoluminescent furan oligoaryls: An approach to improve packing crystallinity of dithiolated aromatics.

The Journal of Physical Chemistry. B, 109(16), 7915–7922.

Chou lab

bottom of page